Hydrogen peroxide
Eskata, Sibnayal (hydrogen peroxide) is a small molecule pharmaceutical. Hydrogen peroxide was first approved as Eskata on 2017-12-14. It is used to treat surgical wound infection in the USA. It has been approved in Europe to treat renal tubular acidosis. It is known to target transient receptor potential cation channel subfamily M member 2 and transient receptor potential cation channel subfamily A member 1.
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Hydrogen peroxide
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| ESKATA | Aclaris Therapeutics | N-209305 DISCN | 2017-12-14 | 1 products, RLD |
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EMA
Brand Name | Status | Last Update |
|---|---|---|
| 100 toothpast e afternoon | unapproved drug other | 2020-12-23 |
| 16oz hydrogen peroxide | OTC monograph not final | 2020-09-25 |
| 3 hydrogen peroxide | OTC monograph not final | 2022-05-05 |
| 3 percent hydrogen peroxide | OTC monograph not final | 2020-10-12 |
| 3% hydrogen peroxide | OTC monograph not final | 2022-01-13 |
| 32oz hydrogen peroxide | OTC monograph not final | 2020-09-25 |
| american red cross 3 hydrogen peroxide | OTC monograph not final | 2022-05-05 |
| american safety first aid antispetic | C200263 | 2024-01-15 |
| antiseptic mouth sore | OTC monograph not final | 2022-01-05 |
| aplicare hydrogen peroxide | C200263 | 2023-10-18 |
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Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| surgical wound infection | — | D013530 | — |
Agency Specific
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ATC Codes
A: Alimentary tract and metabolism drugs
— A01: Stomatological preparations
— A01A: Stomatological preparations
— A01AB: Antiinfectives and antiseptics for local oral treatment
— A01AB02: Hydrogen peroxide
D: Dermatologicals
— D08: Antiseptics and disinfectants
— D08A: Antiseptics and disinfectants
— D08AX: Other antiseptics and disinfectants in atc
— D08AX01: Hydrogen peroxide
— D11: Other dermatological preparations in atc
— D11A: Other dermatological preparations in atc
— D11AX: Other dermatological preparations in atc
— D11AX25: Hydrogen peroxide
S: Sensory organ drugs
— S02: Otologicals
— S02A: Antiinfective drugs, otologic
— S02AA: Antiinfectives
— S02AA06: Hydrogen peroxide
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Clinical
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246 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dentin sensitivity | D003807 | — | — | 3 | 1 | 3 | 2 | 11 | 19 |
| Hypersensitivity | D006967 | HP_0012393 | T78.40 | 2 | — | 1 | 3 | 12 | 18 |
| Tooth discoloration | D014075 | — | K03.6 | — | — | — | 4 | 14 | 18 |
| Tooth bleaching | D014073 | — | — | 1 | — | 2 | 3 | 8 | 14 |
| Covid-19 | D000086382 | — | — | 1 | 4 | — | 4 | 5 | 13 |
| Wounds and injuries | D014947 | — | T14.8 | 1 | 1 | — | 1 | 6 | 9 |
| Infections | D007239 | EFO_0000544 | — | — | 4 | 1 | 1 | 3 | 8 |
| Actinic keratosis | D055623 | — | L57.0 | 1 | 4 | 3 | 1 | — | 8 |
| Seborrheic keratosis | D017492 | EFO_0005584 | L82 | 1 | 4 | 3 | 1 | — | 8 |
| Keratosis | D007642 | — | — | 1 | 4 | 3 | 1 | — | 8 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Warts | D014860 | — | B07 | — | 3 | 4 | — | — | 7 |
| Gingivitis | D005891 | HP_0000230 | K05.10 | — | — | 2 | — | 4 | 6 |
| Acne vulgaris | D000152 | EFO_0003894 | L70 | — | 2 | 1 | — | 2 | 5 |
| Diabetic foot | D017719 | EFO_1001459 | — | — | 1 | 2 | — | 1 | 4 |
| Surgical wound | D000072836 | — | — | — | — | 1 | — | 2 | 3 |
| Wound infection | D014946 | — | — | — | — | 2 | — | 1 | 3 |
| Ulcer | D014456 | MPATH_579 | — | — | — | 2 | — | 1 | 3 |
| Foot ulcer | D016523 | — | — | — | — | 2 | — | 1 | 3 |
| Periodontal pocket | D010514 | EFO_1001393 | — | 1 | — | 1 | — | — | 2 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | 2 | — | — | 2 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Peri-implantitis | D057873 | EFO_1001390 | — | 1 | 1 | — | — | 6 | 8 |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | — | 3 | — | — | 2 | 5 |
| Healthy volunteers/patients | — | — | — | 1 | 2 | — | — | 1 | 4 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 2 | — | — | 1 | 3 |
| Carcinoma | D002277 | — | C80.0 | 1 | 1 | — | — | — | 2 |
| Squamous cell carcinoma | D002294 | — | — | 1 | 1 | — | — | — | 2 |
| Syndrome | D013577 | — | — | 1 | 1 | — | — | 1 | 2 |
| Virus diseases | D014777 | — | B34 | — | 1 | — | — | — | 1 |
| Pharyngeal diseases | D010608 | — | — | — | 1 | — | — | — | 1 |
| Respiratory distress syndrome | D012128 | EFO_1000637 | J80 | 1 | 1 | — | — | — | 1 |
Show 16 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Wound healing | D014945 | GO_0042060 | — | 1 | — | — | — | 4 | 5 |
| Inflammation | D007249 | MP_0001845 | — | 1 | — | — | — | 4 | 5 |
| Dental caries | D003731 | EFO_0003819 | K02 | 1 | — | — | — | 1 | 2 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 1 | — | — | — | 1 | 2 |
| Obstructive lung diseases | D008173 | HP_0006536 | — | 1 | — | — | — | 1 | 2 |
| Dental implants | D015921 | — | — | 1 | — | — | — | 1 | 2 |
| Head and neck neoplasms | D006258 | — | — | 1 | — | — | — | — | 1 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 1 | — | — | — | — | 1 |
| Squamous cell neoplasms | D018307 | — | — | 1 | — | — | — | — | 1 |
| Mucositis | D052016 | EFO_1001898 | — | 1 | — | — | — | — | 1 |
Show 4 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Refractive errors | D012030 | EFO_0003908 | H52.7 | — | — | — | — | 25 | 25 |
| Myopia | D009216 | EFO_0003927 | H52.1 | — | — | — | — | 12 | 12 |
| Presbyopia | D011305 | — | H52.4 | — | — | — | — | 7 | 7 |
| Fistula | D005402 | — | — | — | — | — | — | 7 | 7 |
| Astigmatism | D001251 | EFO_0004222 | H52.2 | — | — | — | — | 7 | 7 |
| Rectal fistula | D012003 | HP_0010447 | K60.3 | — | — | — | — | 6 | 6 |
| Hyperopia | D006956 | EFO_0006310 | H52.0 | — | — | — | — | 5 | 5 |
| Oxidative stress | D018384 | EFO_1001905 | — | — | — | — | — | 4 | 4 |
| Postoperative pain | D010149 | — | G89.18 | — | — | — | — | 4 | 4 |
| Pilonidal sinus | D010864 | HP_0010769 | L05 | — | — | — | — | 3 | 3 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Hydrogen peroxide |
| INN | — |
| Description | Peroxides is compounds of structure ROOR'. It has a role as an oxidising agent. It contains a peroxy group. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | OO |
Identifiers
| PDB | — |
| CAS-ID | 7722-84-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL71595 |
| ChEBI ID | 16240 |
| PubChem CID | 784 |
| DrugBank | — |
| UNII ID | — |
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Eskata – Aclaris Therapeutics
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Hydrogen peroxide
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580 adverse events reported
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